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hematology ana antibody blood differential myelodysplastic nuclear patterns product reactions syndrome anemia blastic cell challenges comparison criticalcare cytoplasmic dendritic differentiation
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
Antinuclear Antibody ... Testing - Nuclear ... #Antibody #Testing ... #differential #diagnosis ... #rheumatology
Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) • Plasmacytoid Dendritic Cells (pDC) Neoplasms • BPDCN • BPDCN
Dendritic Cells (pDC ... • BPDCN like AML ... Zhuoer Xie, MD ... Cell #Neoplasm #diagnosis ... #oncology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
dys- (abnormal) -plastic ... old, ~10,000 new cases ... #Diagnosis #Management ... #treatment #hematology ... #oncology
Antinuclear Antibody Testing - Nuclear Patterns Homogeneous pattern: • SLE, SSc, AIH, JIA • dsDNA, chromatin,
Testing - Nuclear ... pattern: • SSc, PBC ... dots pattern: • PBC ... #differential #diagnosis ... #rheumatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome in APML ... fluid overload, PCC ... Differentiation #Syndrome #APML ... #diagnosis #management ... #hematology #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... • ↓ WBC • ↓ PLT ... #Anemia #oncology ... #hematology #diagnosis ... #management
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... • Anemia • Aplastic ... Treatment: Goals: Treating ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Fluid Responsiveness and Fluid Tolerance Testing - OnePager Summary Fluid resuscitation can be beneficial when required or
Fluid Tolerance Testing ... measurement of CO via a PAC ... cardiac output causes ... #diagnosis #criticalcare ... comparison #challenges #management
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Crossmatch - involves testing ... due to marrow aplasia ... by Nick Mark MD ... #Transfusions #diagnosis ... #management #hematology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
due to marrow aplasia ... false negatives on testing ... infographic by Nick Mark MD ... #Transfusion #diagnosis ... #management #hematology
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