7 results
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
Antinuclear Antibody ... : - SSc, PBC/ ... : - PBC, DM, ... , PBC/SjS OS ... #differential #
Antinuclear Antibody Testing - Nuclear Patterns
Homogeneous pattern: 
 • SLE, SSc, AIH, JIA
 • dsDNA, chromatin,
Antinuclear Antibody ... : • SSc, PBC/SSc ... : • PBC, DM, other ... #differential # ... diagnosis #rheumatology
Antinuclear Antibody Testing Cytoplasmic Patterns
Reticular/AMA: 
 • PBC, SSc, PBC/SSc OS, PBC/SjS OS
 • AMA
Speckled:
 •
Reticular/AMA: • PBC ... , SSc, PBC/SSc OS ... , PBC/SjS OS • ... SjS, SLE, RA, PBC ... #differential #
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
hepatocellular pattern ... though cholestatic pattern ... reported (eg AIH-PBC ... regarding need for treatment ... #Hepatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... initiation • Differential ... fluid overload, PCC ... APML #diagnosis #management ... #hematology #oncology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... www.ncbi.nlm.nih.gov/pmc ... / hypoxemia -> focus ... perfusion - shock->treatments ... before beginning treatment
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis - Differential ... slow onset and pattern ... statins - probably caused ... Other Diseases: • PBC ... #differential #