12 results
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
Antinuclear Antibody Testing ... pattern: - PBC ... : - PBC, SSc ... , PBC/SSc OS, PBC ... Cytoplasmic #Patterns #differential
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
) - Summary PBC ... 30-65 years PBC ... intralobular bile ducts causes ... Proximal limb muscle wasting ... bile ducts Differential
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Liver Enzymes - Differential ... • Ischemia • Autoimmune ... Bile Ducts • PSC ... • Cirrhosis (any ... Diagnosis #Algorithm #Causes
Combination of Skin Findings and Arthritis in Pediatrics Patient - Differential Diagnosis
Malar rash: 
 • A
Patient - Differential ... elevated rim (In POC ... not be seen try focus ... gabrieltalledop #dermatology ... #differential #
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Differential Diagnosis ... Morning stiffness lasting ... weeks) Can Be Caused ... Joint #pain #Differential ... Diagnosis #MSK #rheumatology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
(RA, Temporal arteritis ... Cirrhosis, ETOH, autoimmune ... hepatitis, PBC, ... PSC, Viral hepatitis ... Gap #ProteinGap #differential
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... disease • Non-autoimmune ... deficiencies • Autoimmune ... Antiribosomal P, APLA, PAC ... vein thrombosis Hematologic
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
cell adhesion and ... initiation • Differential ... fluid overload, PCC ... APML #diagnosis #management ... #hematology #oncology
Antinuclear Antibody Testing - Nuclear Patterns
Homogeneous pattern: 
 • SLE, SSc, AIH, JIA
 • dsDNA, chromatin,
Antinuclear Antibody Testing ... pattern: • SSc, PBC ... dots pattern: • PBC ... Nuclear #Patterns #differential ... #diagnosis #rheumatology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
autoimmune disorder ... Hodgkin lymphoma - Autoimmune ... syndrome, rheumatoid arthritis ... life-threatening Differential ... Gravis #diagnosis #management