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diagnosis algorithm extravascular hemolysis intravascular thrombocytosis anemia classification dermatology enlarged erythrocytosis hodgkins lymphoma management mds monoclonal myelodysplasia myelodysplastic nonpalpable palpable
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... - Differential ... thrombocytosis • Polycythemia ... effect following treatment ... #Hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... - Differential ... • PCH • PNH ... Extravascular #Differential ... #Hematology
Causes of Splenomegaly - Differential Diagnosis Algorithm Infectious • Bacterial • Viral (EBV) • Parasitic • Fungal Congestive
- Differential ... disorders (eg. polycythemia ... Serum Sickness Hemolytic ... Spleen #Enlarged #Differential ... #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... hemoglobinuria (PNH ... Extravascular #Causes ... #differential # ... diagnosis #hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... - Differential ... iron deficiency, hemolysis ... thrombocythemia (ET) • Polycythemia ... #hematology #secondary
Causes of Polycythemia (Erythrocytosis) - Differential Diagnosis Algorithm Relative - Normal RBC Mass / Decreased Plasma Volume
Causes of Polycythemia ... Erythrocytosis) - Differential ... Splenomegaly, Increased PMNs ... Erythrocytosis #Differential ... #Hematology
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Polycythemia - Differential ... an underlying cause ... Better call hematology ... #Differential # ... Algorithm #workup #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... DIC/TTP/HUS - Hemolytic ... deficiencies - PNH ... Vasculopathy #Purpura #Differential ... #Diagnosis #hematology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Amyloidosis (CVS+PNS ... • Coombs (-) hemolytic ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
nodosum • Immune hemolytic ... Immunohistochemical studies (to differentiate ... Hodgkin Lymphoma Treatment ... classification #hematology ... #oncology #management
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