13 results
Causes of Arterial and Venous Thrombosis - Differential Diagnosis Framework

STRUCTURAL:
 - PFO: paradoxical emboli
 - Popliteal
Causes of Arterial ... and Venous Thrombosis ... - Differential Diagnosis ... neoplasms - PNH ... #hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
Venous Thrombosis ... - Differential Diagnosis ... coagulation and other causes ... pathophysiology #hematology ... #differential #diagnosis
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Extravascular Causes ... syndrome - Thrombotic ... hemoglobinuria (PNH ... #hematology #anemia
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
autoantibodies that will cause ... vasculopathy, thrombosis ... permeability Diagnosis ... #neurology #rheumatology ... #cerebritis #diagnosis
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
- bleeding or thrombosis ... Treat primary cause ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Amyloidosis (CVS+PNS ... Episodic angioedema+eosinophilia ... Hyperviscosity (Thrombosis ... Paraproteinemias #Hematology ... #Differential #Diagnosis
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
necrosis) - Thrombosis ... arterial and/or venous ... cryoglobulins • Negative causes ... #rheumatology # ... hematology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
also involved), Venous ... syndrome, dural sinus thrombosis ... artery aneurysms Diagnosis ... ) Differential Diagnosis ... signs #symptoms #rheumatology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... count ↑ PLT • ↑ PBS ... • (Peripheral eosinophilia ... #Leukemia #Hematology ... #Oncology #Diagnosis
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
- Differential Diagnosis ... Polyangiitis): • Eosinophilia ... tract, and often causes ... Thrombosis and arterial ... #Rheumatology