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diagnosis differential extravascular hemolysis hemolytic intravascular leukemia nonpalpable oncology palpable purpura rheumatology testing thrombocytosis ulcerative ulcers workup
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... Differential Diagnosis Algorithm ... following EtOH induced thrombocytopenia ... Iron deficiency anemia ... #Causes #Hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Differential Diagnosis Algorithm ... Megakaryopoiesis • Aplastic Anemia ... Heart Valve) #Thrombocytopenia ... #Causes #Hematology
Skin Ulcers by Etiology - Differential Diagnosis Algorithm Physical: • Trauma • Pressure • Radiation Vascular: • Arterial
Differential Diagnosis Algorithm ... • Sickle Cell Anemia ... Ulcers #ulcerative #skinrash ... #dermatology #Differential ... #causes
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
: - Thrombocytopenia ... - Hemolytic anemia ... deficiencies - PNH ... Differential #Diagnosis #hematology ... #nonpalpable #dermatology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... Differential Diagnosis Algorithm ... • PCH • PNH ... immune-complex hemolytic anemia ... #Causes #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... microangiopathy: Thrombotic thrombocytopenic ... hemoglobinuria (PNH ... differential #diagnosis #hematology ... #anemia
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Differential Diagnosis Algorithm ... platelet decrease - PNH ... Schistocytes, thrombocytopenia ... #workup #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... count ↑ PLT • ↑ PBS ... - infiltrates (anemia ... , thrombocytopenia ... #Leukemia #Hematology
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