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diagnosis algorithm acute aptt bleeding bruising lfts prolonged pt transaminitis abscess arterial ascites biliary bilirubin chemistry children cholangitis cholestatic cirrhosis
Table of Causes of Acute Liver Injury #Diagnosis #Hepatology #Acute #Liver #Injury #Causes #Differential #Incidence #Table #Failure
Table of Causes ... of Acute Liver Injury ... #Diagnosis #Hepatology ... Injury #Causes # ... Differential #Incidence
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury Hepatocellular Liver Injury • AST/ALT elevation
) - Causes of Hepatocellular ... Liver Injury ... more specific for hepatic ... Transaminitis #diagnosis #differential ... #hepatology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... / Bruising - Differential ... Destruction • Abnormal ... Iatrogenic) • Liver ... #Hematology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... Liver Injury - Differential ... #Injury #Differential ... #Diagnosis #Causes ... Acute #algorithm #hepatology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
DIC • Severe Liver ... Treat primary cause ... 100mg/dL) - Heparin ... #diagnosis #causes ... treatment #management #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... deficiency • Liver ... deficiencies - PNH ... Cholesterol emboli • Septic ... #Diagnosis #hematology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential ... Algorithm Vascular Causes ... Injury: • Hepatic ... function may be abnormal ... diagnosis #algorithm #hepatology
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... Early liver disease ... Reduced liver synthesis ... #diagnosis #differential ... #hematology #coagulation
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Syndrome, Ischemic Liver ... intravascular coagulation ... Vasculitis • Injury ... pathophysiology #hematology ... #differential #
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Differential Diagnosis ... (e.g. heparin contamination ... • Reduced liver ... amyloidosis #Abnormal ... #hematology #coagulation
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