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diagnosis differential algorithm management hemolysis intravascular oncology extravascular mcv rheumatology workup agglutinin alkaline alp approach arterial cirrhosis coagulation cold common
Hemolytic anemia in Wilson's disease #Wilsons #Disease #hemolytic #anemia #Hematology #pathophysiology
Hemolytic anemia ... in Wilson's disease ... #Wilsons #Disease ... #hemolytic #anemia ... #Hematology #pathophysiology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... anemia): ... hemoglobinuria (PNH ... differential #diagnosis #hematology ... #anemia
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... • Bleeding • Hemolysis ... #MCV #Classification ... Diagnosis #Algorithm #Causes ... #Hematology
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Diagnosis for Hemolytic ... Anemia Intrinsic ... : • Liver disease ... #classification ... #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... • PCH • PNH ... anemia • ... Diagnosis #Algorithm #Causes ... #Hematology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
-100): • Non-hemolytic ... , CKD • Hemolytic ... PK, HbC, HbSS, PNH ... Non-megaloblastic: Liver disease ... Differential #Diagnosis #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... platelet decrease - PNH ... , Hemoglobin H disease ... #Anemia #Differential ... Algorithm #workup #hematology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... , Drugs, Liver Disease ... , PNH 3) Internal ... Defects: Sickle cell anemia ... Differential #Diagnosis #hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Overall Approach to Anemia ... Disease • Marrow ... #Classification ... Diagnosis #Algorithm #Causes ... #Hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Bone marrow disease ... DIC/TTP/HUS - Hemolytic ... anemia - Splenomegaly ... deficiencies - PNH ... Differential #Diagnosis #hematology
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