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diagnosis management differential algorithm aplastic leukemia myelodysplastic pancytopenia syndrome workup activation bariatric bypass chronic classification cll complications encephalopathy gastric gastroenterology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
old, ~10,000 new cases ... cytopenias (usually anemia ... only curative treatment ... Myelodysplastic #Syndrome #MDS ... #hematology #oncology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Treatment: • Consider ... Can progress to MDS ... • Associated PNH ... diagnosis #management #treatment ... #hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
PNH 2. ... Drugs Nutritional ... Acquired Aplastic Anemia ... • Hypoplastic MDS ... Diagnosis #Algorithm #Hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
PNH 2. ... Drugs Nutritional ... Acquired Aplastic Anemia ... • Hypoplastic MDS ... Diagnosis #Algorithm #Hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... myelodysplastic syndrome (MDS ... Hypocellular/Hypoplastic MDS ... Treatment: ... #oncology #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
5) Symptoms of anemia ... marrow failure with anemia ... Lauren Banaszak, MD ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... skin that are caused ... Platelet Disorders • Nutritional ... Syndromes #diagnosis #hematology ... #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... count ↑ PLT • ↑ PBS ... - infiltrates (anemia ... #Leukemia #Hematology ... #Oncology #Diagnosis
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
nervous system (CNS ... with leukopenia, anemia ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology ... #Rheumatology
Hepatic Encephalopathy Treatment • Lactulose: - Oral liquid, 30-45mL 2-4x/day, titrated to 2-4
Encephalopathy Treatment ... swallow) - Via enema ... For refractory cases ... Encephalopathy #Treatment ... #management #hepatology
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