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diagnosis differential aflp hellp intravascular obstetrics table thrombocytopenia ttphus arterial dermatology disseminated embolism extravascular hemolysis hemolytic leukemia management nonpalpable obgyn
Thrombocytopenia and Pregnancy Three syndromes in the critically ill pregnant woman who presents with coagulation defects. 1) HELLP
presents with coagulation ... schistocytes, DIC ... child * Severe cases ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP) Three syndromes in
presents with coagulation ... schistocytes, DIC ... child * Severe cases ... AFLP #obstetrics #hematology ... diagnosis #table #comparison
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
dysfunction (25%) • Hepatic ... Treat primary cause ... 100mg/dL) - Heparin ... #diagnosis #causes ... treatment #management #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Hemolytic anemia ... Defects: • DIC ... deficiencies - PNH ... Cholesterol emboli • Septic ... Differential #Diagnosis #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... intravascular coagulation ... (DIC) - HELLP ... differential #diagnosis #hematology ... #anemia
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Intravenous Drug Use • Pregnancy ... Hyperhomocysteinemia - Heparin-induced ... intravascular coagulation ... and other causes ... pathophysiology #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... - infiltrates (anemia ... Fibrinolysis & DIC ... #Leukemia #Hematology ... #Oncology #Diagnosis
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