12 results
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
Arterial Thrombosis - Differential ... Hyperhomocysteinemia - Heparin-induced ... coagulation and other causes ... Venous #Arterial #pathophysiology ... #hematology #differential
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... Treat primary cause ... Coagulation #diagnosis #causes ... #treatment #management ... #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... deficiencies - PNH ... Cholesterol emboli • Septic ... Vasculopathy #Purpura #Differential ... #Diagnosis #hematology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... = nonspecific (nausea ... infiltration) Differential ... Liver #Pregnancy #hepatology ... #pathophysiology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... myalgias, HoTN, edema ... initiation • Differential ... APML #diagnosis #management ... #hematology #oncology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... intralobular bile ducts causes ... bile ducts Differential ... malignancies, Hepatic ... diagnosis #workup #hepatology
Hepatic Encephalopathy Treatment
 • Lactulose:
    - Oral liquid, 30-45mL 2-4x/day, titrated to 2-4
Hepatic Encephalopathy ... swallow) - Via enema ... For refractory cases ... Encephalopathy #Treatment #management ... #hepatology
Causes of Fever in the Immunocompromised Host - Differential Diagnosis Algorithm
Structural Defect - Asplenia/HypospIenism
 • Bacteremia/Septic
Causes of Fever ... Immunocompromised Host - Differential ... • Bacteremia/Septic ... jirovecii • CNS ... #Hematology
VIBES Mnemonic - Cirrhosis Management Checklist

V - Volume (Ascites, HRS)
	- Evaluate for Ascites, Edema, Hydrothorax, Hepatorenal
Mnemonic - Cirrhosis Management ... Evaluate for Ascites, Edema ... beta-blockers E - Hepatic ... Vaccines (HAV, HBV, PNA ... #Diagnosis #Hepatology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
of about three cases ... Lymphoma (90-95% of cases ... Immunohistochemical studies (to differentiate ... classification #hematology ... #oncology #management