11 results
diagnosis differential abnormal pt arterial intravascular thrombosis venous algorithm anemia bleeding bruising clots dermatology dic disorders embolism emergencies evaluation extravascular
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... Disseminated intravascular ... #Prolonged #Causes ... #differential #hematology ... #coagulation
Causes of Prolonged PT (INR), Prolonged PTT • Prolonged PT (INR), Prolonged PTT • Prolonged PT
Causes of Prolonged ... PTT • Prolonged ... PTT • Prolonged ... Diagnosis #Algorithm #Causes ... #Hematology #coagulation
How to Evaluate an Abnormal APTT Step 1: Is the PT or APTT Artifactually Prolonged? Step 2: Is
Artifactually Prolonged ... K Antagonists, Heparin ... to identify the cause ... of Prolonged APTT ... #hematology #evaluation
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Disseminated Intravascular ... Thrombocytopenia • Prolonged ... Treat primary cause ... #diagnosis #causes ... treatment #management #hematology
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
(e.g. heparin contamination ... hemorrhage • Disseminated ... #Prolonged #Causes ... #differential #hematology ... #coagulation
Causes of Arterial and Venous Thrombosis - Differential Diagnosis Framework STRUCTURAL: - PFO: paradoxical emboli - Popliteal
Causes of Arterial ... endocarditis) - Disseminated ... intravascular coagulation ... neoplasms - PNH ... Diagnosis #clots #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
vascular disorders, coagulation ... Platelet defects • Coagulation ... deficiencies - PNH ... Cholesterol emboli • Septic ... Differential #Diagnosis #hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Hyperhomocysteinemia - Heparin-induced ... thrombocytopenia - Disseminated ... intravascular coagulation ... and other causes ... pathophysiology #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... anemia): - Disseminated ... intravascular coagulation ... hemoglobinuria (PNH ... differential #diagnosis #hematology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
Acquired: • Heparin ... the PT remains prolonged ... liver failure, disseminated ... discern these causes ... Differential #Diagnosis #Hematology
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