21 results
How to Evaluate an Abnormal APTT
Step 1: Is the PT or APTT Artifactually Prolonged?
Step 2: Is
Artifactually Prolonged ... K Antagonists, Heparin ... to identify the cause ... of Prolonged APTT ... #diagnosis #hematology
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury
Hepatocellular Liver Injury
 • AST/ALT elevation
Enzymes (LFTs) - Causes ... Cholestatic Liver Injury ... Hepatocellular Liver Injury ... more specific for hepatic ... #differential #hepatology
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Causes of Abnormal ... unfractionated heparin ... Pre-analytical cause ... e.g. heparin ... #differential #hematology
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Diagnosis for a Prolonged ... Causes include : ... (e.g. heparin contamination ... thrombin inhibitors, heparin ... #differential #hematology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Causes of Acute ... Liver Injury - Differential ... Vasculature • Hepatic ... Congestion/CHF • Hepatic ... Acute #algorithm #hepatology
Causes of Pleural Effusion - Differential Diagnosis Algorithm
Transudate - Hydrostatic
 • Congestive heart failure
 • Constrictive
Causes of Pleural ... Diaphragmatic: • Hepatic ... • Postcardiac injury ... Diagnosis #Algorithm #Hepatology ... #causes
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Thrombocytopenia • Prolonged ... Treat primary cause ... 100mg/dL) - Heparin ... Coagulation #diagnosis #causes ... treatment #management #hematology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Induced Liver Injury ... for alternative causes ... liver disease, Hepatic ... presentation: Hepatic ... Diagnosis #Algorithm #hepatology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
Hyperhomocysteinemia - Heparin-induced ... coagulation and other causes ... - COVID-19 - PNH ... Vasculitis • Injury ... pathophysiology #hematology
Childhood Immunization Schedule: Why we immunize
 • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
metabolites induce injury ... replicates within CNS ... invade URT & via hematologic ... , altered LOC; septic ... CNS and hematologic