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diagnosis differential syndrome treatment algorithm anticoagulation antinxp2 antinxp2dm apml arterial ascites cancer checklist childhood cirrhosis coagulation dermatology dermatomyositis dic differentiation
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Thrombocytopenia • Prolonged ... protein C and S Pathophysiology ... Treat primary cause ... #treatment #management ... #hematology
Childhood Immunization Schedule: Why we immunize • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
muscle spasms lead ... invade URT & via hematologic ... , altered LOC; septic ... CNS and hematologic ... peds #pediatrics #pathophysiology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Hyperhomocysteinemia - Heparin-induced ... coagulation and other causes ... - COVID-19 - PNH ... Venous #Arterial #pathophysiology ... #hematology #differential
Treatment algorithm for VTE in Malignancy (A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
initiated after a LMWH lead-in ... low-molecular-weight heparin ... Anticoagulation #Management ... #Hematology #Oncology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... Lysis Syndrome: • Pathophysiology ... TLS #diagnosis #management ... #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
ATRA treatment Pathophysiology ... myalgias, HoTN, edema ... APML #diagnosis #management ... #hematology #oncology
Hepatic Encephalopathy Treatment • Lactulose: - Oral liquid, 30-45mL 2-4x/day, titrated to 2-4
Hepatic Encephalopathy ... swallow) - Via enema ... For refractory cases ... Encephalopathy #Treatment #management ... #hepatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
activity • ↓ LAP ... -> AML: Blast crises ... count ↑ PLT • ↑ PBS ... #Leukemia #Hematology ... #Oncology #Diagnosis
VIBES Mnemonic - Cirrhosis Management Checklist V - Volume (Ascites, HRS) - Evaluate for Ascites, Edema, Hydrothorax, Hepatorenal
Mnemonic - Cirrhosis Management ... Evaluate for Ascites, Edema ... beta-blockers E - Hepatic ... Vaccines (HAV, HBV, PNA ... #Diagnosis #Hepatology
Common Malignancies That Cause Ascites The most common malignancies causing ascites are ovarian cancer, pancreatic cancer, gastric
Malignancies That Cause ... Cancer - Can lead ... hypertension or hepatic ... Differential #Diagnosis #Hepatology ... #oncology
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