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differential management algorithm hemeonc leukemia aplastic chronic cll lymphocytic myelodysplastic pancytopenia syndrome activation bariatric bypass cell classification complications disorders emergencies
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
old, ~10,000 new cases ... cytopenias (usually anemia ... Myelodysplastic #Syndrome #MDS ... #treatment #hematology ... #oncology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Diagnosis: • Pancytopenia ... Treatment: • Consider ... Can progress to MDS ... • Associated PNH ... #treatment #hematology
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
40 ml/min A - Anemia ... Causes of false- ... amyloidosis Other causes ... Gammopathies #MGUS #diagnosis ... #hematology #oncology
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Pancytopenia - Workup ... PNH 2. ... Acquired Aplastic Anemia ... • Hypoplastic MDS ... #Algorithm #Hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Pancytopenia - Workup ... PNH 2. ... Acquired Aplastic Anemia ... • Hypoplastic MDS ... #Algorithm #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... for workup, including ... hemolysis, deficiency anemia ... Rebound effect from treatment ... #Algorithm #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... and Workup History ... changes), high MCV anemia ... #Causes #Workup ... #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
5) Symptoms of anemia ... fludarabine) 3) Monoclonal ... Lauren Banaszak, MD ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Can Feature A Monoclonal ... Amyloidosis (CVS+PNS ... (-) hemolytic anemia ... Paraproteinemias #Hematology ... #Diagnosis #Oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... Hypocellular/Hypoplastic MDS ... Treatment: ... #oncology #hematology ... #diagnosis #management
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