10 results
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Thrombocytopenia ... (AFLP) Three syndromes ... child * Severe cases ... #Thrombocytopenia ... #obstetrics #hematology
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Thrombocytopenia ... child * Severe cases ... @Bloodman #Thrombocytopenia ... #HELLP #AFLP #Obstetrics ... #OBGyn #Hematology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Differential Diagnosis Algorithm ... • Wilson's • Pregnancy ... - AFLP, HELLP ... Others #LFTs #Hepatology ... #Causes
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Fatty Liver of Pregnancy ... (AFLP) Pathophysiology ... = nonspecific (nausea ... iMedEducation #AFLP ... #hepatology #obstetrics
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
Differential Diagnosis Algorithm ... Intestine - Other causes ... - Drugs - Pregnancy ... Differential #Diagnosis #Algorithm ... #hepatology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
Intravenous Drug Use • Pregnancy ... Heparin-induced thrombocytopenia ... coagulation and other causes ... Venous #Arterial #pathophysiology ... #hematology #differential
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Most cases diagnosed ... membrane into the CNS ... collection with EDTA Pathophysiology ... Phosphatase: • Other causes ... Hyophosphatasia #hepatology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... Thromboembolism (7%) • CNS ... Treat primary cause ... Coagulation #diagnosis #causes ... treatment #management #hematology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Differential Diagnosis Algorithm ... Vascular Causes ... melanoma, myeloma • Pregnancy ... differential #diagnosis #algorithm ... #hepatology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... intralobular bile ducts causes ... obstruction • ALP ... cholestasis of pregnancy ... diagnosis #workup #hepatology