10 results
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
Heparin-induced thrombocytopenia ... coagulation and other causes ... - COVID-19 - PNH ... #pathophysiology ... #hematology #differential
Causes of Thrombocytopenia - Differential Diagnosis Framework
Decreased Production:
 - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Causes of Thrombocytopenia ... HCV, EBV, CMV - Bacterial ... sequestration: - Cirrhosis ... Medicine @SCVMCMed #Thrombocytopenia ... Diagnosis #Framework #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
inflammation • Thrombocytopenia ... : - Thrombocytopenia ... deficiencies - PNH ... gangrenosum • Bacterial ... Differential #Diagnosis #hematology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... intralobular bile ducts causes ... obstruction • ALP ... Hepatic amyloidosis, Bacterial ... diagnosis #workup #hepatology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Most cases diagnosed ... membrane into the CNS ... collection with EDTA Pathophysiology ... Phosphatase: • Other causes ... Hyophosphatasia #hepatology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... Thromboembolism (7%) • CNS ... Treat primary cause ... Coagulation #diagnosis #causes ... treatment #management #hematology
VIBES Mnemonic - Cirrhosis Management Checklist

V - Volume (Ascites, HRS)
	- Evaluate for Ascites, Edema, Hydrothorax, Hepatorenal
VIBES Mnemonic - Cirrhosis ... Evaluate for Ascites, Edema ... Transplant) - RUQUS + AFP ... Vaccines (HAV, HBV, PNA ... Management #Diagnosis #Hepatology
TAFRO

TAFRO syndrome was first described in 2010, standing for:
- Thrombocytopenia
- Anasarca
- Fever
- Reticulin fibrosis
- Organomegaly

TAFRO syndrome
including acid fast bacterial ... IGG4 - Hepatic cirrhosis ... cell lymphoma Pathophysiology ... histopathologic changes in LNs ... diagnosis #management #rheumatology
Hepatorenal Syndrome (HRS)

Definition:
• Functional, potentially reversible kidney impairment.
• Occurs in advanced liver disease: cirrhosis, severe alcoholic
liver disease: cirrhosis ... • Caused by splanchnic ... Pathophysiology: ... • ↓ Effective arterial ... Hepatorenal #Syndrome #Hepatology
Hepatopulmonary Syndrome - Illness Script
HPS is a pulmonary disorder of chronic liver disease characterized by a
abnormalities PATHOPHYSIOLOGY ... leads to impaired arterial ... arteriovenous shunting causes ... • Stigmata of cirrhosis ... #diagnosis #hepatology