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diagnosis management differential oncology rheumatology syndrome classification cns dermatology hepatic intravascular activation aids algorithm alkaline alp antinxp2 antinxp2dm bariatric bypass
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... disorders • Celiac disease ... effect following treatment ... Iron deficiency anemia ... #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... hemoglobinuria (PNH ... Extravascular #Causes ... differential #diagnosis #hematology ... #anemia
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
PT, aPTT(liver disease ... (CVID, WAS), (neurologic ... changes), high MCV anemia ... bypass), LFT (liver disease ... #Workup #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Meningitis, Myelopathy, Encephalopathy ... Cerebrovascular Disease ... autoantibodies that will cause ... Puncture, EEG Treatment ... #neurology #rheumatology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Bone marrow disease ... - Hemolytic anemia ... Von Willebrand disease ... deficiencies - PNH ... Differential #Diagnosis #hematology
Hepatic Encephalopathy Treatment • Lactulose: - Oral liquid, 30-45mL 2-4x/day, titrated to 2-4
Hepatic Encephalopathy ... Treatment • Lactulose ... swallow) - Via enema ... For refractory cases ... #hepatology
Hepatic Encephalopathy - Diagnosis and Management Summary Definition: • Alteration in brain function manifested by neuropsychiatric symptoms
Hepatic Encephalopathy ... of neurologic/cognitive ... over course of disease ... LizzieAbyMD #Hepatic #Encephalopathy ... #hepatology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
Antimicrobial treatment ... + mass effect/Edema ... Demyelinating disease ... caused by the JC ... - +mass effect/Edema
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Posterior Reversible Encephalopathy ... may precede the neurologic ... Shock, Autoimmune disease ... the underlying cause ... • Treatment of
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
• Severe Liver Disease ... + Bleeding Treatment ... Treat primary cause ... #treatment #management ... #hematology
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