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diagnosis rheumatology differential treatment dermatology extravascular hemolysis sle anemia antinxp2 antinxp2dm atlas basics cardiology cerebritis chf clinical cns coagulation criticalcare
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... Differential Diagnosis Algorithm ... • PCH • PNH ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Causes Intravascular ... hemoglobinuria (PNH ... usually IgG) (e.g. lupus ... #Causes #differential ... #diagnosis #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... autoantibodies that will cause ... Erythematosus #SLE #CNS ... #neurology #rheumatology ... cerebritis #diagnosis #management
Hydroxychloroquine Serum Measurement in SLE • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
suspected) • In case ... • Special cases ... Measurement #SLE #rheumatology ... #pharmacology # ... levels #lupus #management
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Disseminated Intravascular ... Treat primary cause ... #Disseminated #Intravascular ... #treatment #management ... #hematology
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
JVD, Orthopnea/PND ... the determined cause ... #differential #algorithm ... #management #cardiology ... icu #clinical #pharmacology
Primary Dermatological Lesions Primary lesions are physical changes in the skin considered to be caused directly by
considered to be caused ... flat macules of extravascular ... lesions that contain pus ... area of dermal oedema ... #Diagnosis #Dermatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... Xerostomia • Dental caries ... Nephrogenic DI Hematologic ... lubricants • Pharmacologic ... #Diagnosis #Management
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
generalized subcutaneous edema ... Pts have more ... Muscle atrophy may cause ... Dermatomyositis #diagnosis #management ... dermatology
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
including systemic lupus ... cell lymphoma - Intravascular ... histopathologic changes in LNs ... TAFRO #diagnosis #management ... #rheumatology #
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