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diagnosis rheumatology table sle treatment erythematosus hcq hydroxychloroquine hyperkalemia lr nephrology ns potassium systemic adverseeffects agents algorithm antinxp2 antinxp2dm antiobesity
Hydroxychloroquine Serum Measurement in SLE • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
200ng/mL Best indications ... • Special cases ... Measurement #SLE #rheumatology ... #pharmacology # ... levels #lupus #management
Considerations for Crystalloids - 0.9% NS vs LR vs Plasma-Lyte - Causes hyperkalemia? - Safe to
Plasma-Lyte - Causes ... - Causes lactic ... - Can cause a NAGMA ... #Crystalloids #pharmacology ... #indications #comparison
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... autoantibodies that will cause ... Erythematosus #SLE #CNS ... #neurology #rheumatology ... cerebritis #diagnosis #management
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Discontinuation of causal ... Usual therapeutic management ... #sle #comparison ... #table #rheumatology ... #diagnosis #management
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Malignancy (e.g. hematologic ... lower extremity edema ... proteinuria, dependent edema ... • May involve PNS ... activation and/or medications
Lactated Ringers (LR) vs Normal Saline (NS) - Comparison Composition of LR: • Sodium 130 mEq/L •
) - Comparison ... shift • Saline Causes ... • Saline May Cause ... • Increases Edema ... #comparison #pharmacology
Hydroxychloroquine - Risks and Benefits in Lupus Benefits: ↓ Disease activity, ↓ Flare, ↓ Damage, ↓ Corticosteroid dose,
and Benefits in Lupus ... recommended with other medications ... Risks #Benefits #Lupus ... #pharmacology # ... #sideeffects #rheumatology
Intern Pocket Cards - Inpatient Bowel Regimen Guide Osmotic agents (draws water into bowel, thereby loosening stool
Polyethylene glycol - Nausea ... • Tap water enema ... Guide #Inpatient #medications ... #constipation #pharmacology ... agents #internship #comparison
Potassium-Binding Agents to Treat Hyperkalemia Sodium zirconium cyclosilicate (Lokelma): • Mechanism: Preferentially captures K in exchange for
Side Effects: Edema ... hypokalemia); nausea ... #Hyperkalemia #medications ... #pharmacology # ... table #comparison
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
irrigation • Management ... Acute pulmonary edema ... Kidney stones caused ... Diuresis #Nephrology #Pharmacology ... #Medications #Table
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