15 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... autoantibodies that will cause ... Erythematosus #SLE #CNS ... #neurology #rheumatology ... cerebritis #diagnosis #management
Hydroxychloroquine Serum Measurement in SLE
 • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
200ng/mL Best indications ... • Special cases ... Measurement #SLE #rheumatology ... #pharmacology # ... levels #lupus #management
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Malignancy (e.g. hematologic ... lower extremity edema ... proteinuria, dependent edema ... • May involve PNS ... activation and/or medications
Hydroxychloroquine - Risks and Benefits in Lupus
Benefits:
↓ Disease activity, ↓ Flare, ↓ Damage, ↓ Corticosteroid dose,
and Benefits in Lupus ... recommended with other medications ... Risks #Benefits #Lupus ... #pharmacology # ... #sideeffects #rheumatology
Management of SIADH
Treat underlying cause:
 • Causes can include pain, primary lung pathology, post-operative phenomenon, medications,
Management of SIADH ... post-operative phenomenon, medications ... bolus of 0.9% NS ... SatyaPatelMD #SIADH #Management ... #hyponatremia #nephrology
SIADH Treatment Options
1. Treat underlying cause of SIADH: Pain, Primary lung pathology, Post-operative phenomenon, Medications, Basically
Treat underlying cause ... Post-operative phenomenon, Medications ... administered • This can cause ... SatyaPatelMD #SIADH #Management ... #hyponatremia #nephrology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
irrigation • Management ... Kidney stones caused ... Excretion #Diuresis #Nephrology ... #Pharmacology # ... Medications #Table
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Etiology: • Medications ... only if no clear cause ... STOP offending medications ... caution in HTN & edema ... Treatment #potassium #nephrology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Electrolyte abnormality, Medication ... the underlying cause ... with AEDs until cause ... Syndrome #diagnosis #management ... #neurology
Emergency Treatment Algorithm for Convulsive Status Epilepticus
1. ABCDEFG (ABC's and Don't Ever Forget the Glucose)
2. Airway:
for reversible cause ... Refractory medications ... Treatment #Algorithm #Management ... #Neurology #Pharmacology