33 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
of Systemic Lupus ... Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... autoantibodies that will cause ... cerebritis #diagnosis #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
lupus erythematosus ... (CNS) dysfunction ... lupus erythematosus ... #Diagnosis #Management ... #Hematology #Rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... ) Suspect: Clinical ... Clinical Features ... • May involve PNS ... activation and/or medications
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... 40, F:M 9:1 • Clinical ... Positive in 60-80% of cases ... #Systemic #Erythematosus ... #Summary #rheumatology
Hydroxychloroquine Serum Measurement in SLE
 • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
200ng/mL Best indications ... • Special cases ... Measurement #SLE #rheumatology ... #pharmacology # ... levels #lupus #management
Drug Reaction with Eosinophilia and Systemic Signs (DRESS Syndrome): Formerly known as drug hypersensitivity reaction, DRESS
represents
Eosinophilia and Systemic ... Signs (DRESS Syndrome ... allergic reaction to medication ... (in this case Tegretol ... #Dermatology #SkinRash
Drug Reaction with Eosinophilia and Systemic Signs (DRESS Syndrome): Formerly known as drug hypersensitivity reaction, DRESS
represents
Eosinophilia and Systemic ... Signs (DRESS Syndrome ... allergic reaction to medication ... (in this case Tegretol ... #Dermatology #SkinRash
Behcet's Syndrome - Treatment
Ulcers:
 • Treatment: Topical steroids
 • Prevention: Colchicine
 • Azathioprine for refractory disease
Arthritis:
Behcet's Syndrome ... Behcets #disease #Syndrome ... #Treatment #management ... #pharmacology # ... rheumatology
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
Optica (NMO) - Clinical ... involvement: Intractable nausea ... pain • Extra-CNS ... autoimmune disorders (Systemic ... lupus erythematosus
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Discontinuation of causal ... months to years) Systemic ... 40, F:M 9:1 • Clinical ... #diagnosis #management