10 results
Tranexamic Acid - Indications and Pharmacology
Pharmacokinetics:
 • MOA: Inhibits plasminogen activation to plasmin & inhibits fibrinolysis
and Pharmacology ... : Urine Common Uses ... arterial thrombotic events ... #Pharmacology # ... hematology
Intern Pocket Cards - Inpatient Bowel Regimen Guide
Osmotic agents (draws water into bowel, thereby loosening stool
Guide Osmotic agents ... • Tap water enema ... Guide #Inpatient #medications ... #constipation #pharmacology ... #internship #comparison
Hydroxychloroquine Serum Measurement in SLE
 • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
200ng/mL Best indications ... • Special cases ... Measurement #SLE #rheumatology ... #pharmacology # ... levels #lupus #management
Treatment of giant cell arteritis (GCA)

1st Line Strategy - GC 0.7 mg/kg/day, except for:
 • Aortitis
start GC-sparing agents ... MTX or TCZ in case ... GCA #Treatment #Management ... #Relapses #Indications ... #rheumatology #2ndline
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Potassium-Binding Agents ... Side Effects: Edema ... #Hyperkalemia #medications ... #pharmacology # ... table #comparison
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Diuretics and Agents ... irrigation • Management ... Kidney stones caused ... Diuresis #Nephrology #Pharmacology ... #Medications #Table
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
and petechiae Causes ... - Antithyroid medications ... salts • Chemical Agents ... Anemia #oncology #hematology ... #diagnosis #management
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... Nephrogenic DI Hematologic ... lubricants • Pharmacologic ... Sjogrens #Syndrome #Rheumatology ... #Diagnosis #Management
Antiobesity Drugs and Their Effects
Orlistat
 • GI Lipase inhibitor
 • Reduces lipid absorption
 • Toxicity: Decreased
Norepinephrine release in CNS ... + antiseizure agent ... Antiobesity #Drugs #medications ... #pharmacology # ... management
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
generalized subcutaneous edema ... Pts have more ... Muscle atrophy may cause ... Dermatomyositis #diagnosis #management ... #rheumatology #