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diagnosis rheumatology treatment lupus dermatology hyperkalemia potassium table antinxp2 antinxp2dm aspirin atopic binders binding cardiology cardiomyopathy dermatitis dermatomyositis effects erythematosus
Hydroxychloroquine Serum Measurement in SLE • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
Measurement in SLE ... 200ng/mL Best indications ... #rheumatology # ... pharmacology #levels ... #lupus #management
Salicylate Toxicity - Diagnosis and Management Consider if: 1) Patient is hot and altered 2) You see tachypnea with
altered 2) You see ... no respiratory cause ... like DKA, sepsis, PNA ... Diaphoresis, Pulmonary edema ... Toxic Salicylate Level
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Discontinuation of causal ... Lupusreference #druginduced ... #lupus #sle #comparison ... #table #rheumatology ... #diagnosis #management
Atopic Dermatitis - Topical Treatment Options First Line: Topical Corticosteroids - High Potency: Betamethasone
After non-pharmacologic ... has a different level ... than roflumilast (see ... #Pharmacology # ... Dermatology #Management
Lactated Ringers (LR) vs Normal Saline (NS) - Comparison Composition of LR: • Sodium 130 mEq/L •
) - Comparison ... shift • Saline Causes ... • Saline May Cause ... Saline Increases Levels ... #comparison #pharmacology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
lower extremity edema ... proteinuria, dependent edema ... • May involve PNS ... antibodies, Complement levels ... activation and/or medications
Potassium-Binding Agents to Treat Hyperkalemia Sodium zirconium cyclosilicate (Lokelma): • Mechanism: Preferentially captures K in exchange for
Side Effects: Edema ... Dosing: 15 g (4 level ... #Hyperkalemia #medications ... #pharmacology # ... table #comparison
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Etiology: • Medications ... Renin/Aldosterone levels ... only if no clear cause ... and Elimination (see ... caution in HTN & edema
Peripartum Cardiomyopathy - Summary 1. Definition • Towards the end of pregnancy to 5 months postpartum
exclude other causes ... through ↑ sFLT1 levels ... (levels ↑ in pre-eclampsia ... , LE edema • Minority ... of Pts: cardiogenic
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... Hypocomplementemia • Can cause ... Nephrogenic DI Hematologic ... lubricants • Pharmacologic ... #Diagnosis #Management
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