14 results
diagnosis management aplastic dermatology hemeonc mds myelodysplastic antinxp2 antinxp2dm behcet chronic classification cll dermatomyositis differential disease emergencies erythematosus gap globulin
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... old, ~10,000 new cases ... cytopenias (usually anemia ... transformation to acute leukemia ... #hematology #oncology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Illness Script Signs ... Treatment: • Consider ... to MDS or acute leukemia ... • Associated PNH ... #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... • Neutropenia, anemia ... microglobulin Treatment ... #diagnosis #workup ... #oncology #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... develop leukostasis syndrome ... - infiltrates (anemia ... • Tumor lysis syndrome ... #Hematology #Oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... and petechiae Causes ... virus (EBV) • Leukemia ... Treatment: ... #oncology #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... • Hairy Cell Leukemia ... Workup: • Complete ... #diagnosis #hematology ... #oncology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Episcleritis Signs ... Causes: - Idiopathic ... , breast CA - Hematologic ... Treatment: - Systemic ... #oncology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
basal ganglia, CNS ... tears, Ischemia, Leukemia ... Arthritis, AS Treatment ... diagnosis #management #signs ... #symptoms #rheumatology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
full infectious work-up ... days → add fungal work-up ... ): - Hematologic ... Treat underlying cause ... Usually myeloid leukemias
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
lower extremity edema ... • May involve PNS ... lymphopenia, low PLT • Anemia ... Hodgkin lymphoma and leukemia ... Erythematosus #Diagnosis #Rheumatology
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