12 results
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
Antineutrophil cytoplasmic antibodies ... ANCA-Associated Vasculitis ... Renal-limited vasculitis ... Antineutrophil #antibodies ... #diagnosis #rheumatology
Eosinophilic Granulomatosis with Polyangiitis (EGPA) - ANCA Vasculitis Management Algorithm - ACR/VF 2021 Guidelines
 • Active
(EGPA) - ANCA Vasculitis ... Management Algorithm ... alone in select pts ... #ANCA #Vasculitis ... Guidelines #algorithm #rheumatology
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
disease c-ANCA - Vasculitis ... Microscopic polyangiitis ... diseases #diagnosis #table ... #rheumatology # ... antibodies
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Autoimmune ANCA vasculitis ... palpable purpura 2/2 vasculitis ... EGPA) • Auto-antibodies ... Goodpasture's cause ... differential #diagnosis #management
Kawasaki Disease (KD) - Diagnosis and Management Summary

Kawasaki Disease (KD) is the most common vasculitis of
the most common vasculitis ... Mucositis, Rash, Hand edema ... , Cough • +/-Nausea ... palms or soles, edema ... #rheumatology #
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Vasculitis and Vasculitides ... • Microscopic Polyangiitis ... tract, and often causes ... C-ANCA) pattern: antibodies ... differential #diagnosis #rheumatology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
Antiphospholipid antibodies ... coagulation and other causes ... - COVID-19 - PNH ... - Vasculitis ... pathophysiology #hematology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
: Microscopic polyangiitis ... Granulomatosis with Polyangiitis ... Granulomatosis with Polyangiitis ... tract, and often causes ... Differential #Diagnosis #Rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Non-autoimmune rheumatologic ... lower extremity edema ... • May involve PNS ... 1, SCL-70, RNP antibodies ... Erythematosus #Diagnosis #Rheumatology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
) • Cutaneous vasculitis ... Nephrogenic DI Hematologic ... : 2% Systemic Vasculitis ... Sjogrens #Syndrome #Rheumatology ... #Diagnosis #Management