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diagnosis sle systemic treatment druginduced activation antinxp2 antinxp2dm cerebritis clues cns comparison dermatology dermatomyositis dil hyperkalemia k macrophage mas nephrology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... • Immunologic Workup ... Positive in 60-80% of cases ... #Systemic #Erythematosus ... #Summary #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus ( ... autoantibodies that will cause ... #Erythematosus ... #rheumatology # ... cerebritis #diagnosis #management
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Non-autoimmune rheumatologic ... Malignancy (e.g. hematologic ... lower extremity edema ... • May involve PNS ... #Diagnosis #Rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... Erythematosus ( ... • Immunologic Workup ... sle #comparison #table ... #rheumatology #
Top 10 situations when to think about lupus 1) Inflammatory joint pain (especially in the wrists and
to think about lupus ... rosacea) 3) Limb oedema ... pericarditis » is...lupus ... #system #erythematosus ... #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
erythematosus ... nervous system (CNS ... erythematosus [ ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
S/Sx: Most pts ... reabsorption) Workup ... only if no clear cause ... Elimination (see Table ... caution in HTN & edema
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
Drug Induced Lupus ... • Immunologic Workup ... Discontinuation of causal ... #DIL #rheumatology ... diagnosis #treatment #management
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
Pts have more ... • Erythematous ... Muscle atrophy may cause ... Dermatomyositis #diagnosis #management ... #rheumatology #
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
including systemic lupus ... erythematosus ( ... histopathologic changes in LNs ... TAFRO #diagnosis #management ... #rheumatology #
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