15 results
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
hemorrhagic skin lesions ... Kasabach-Merritt syndrome ... deficiencies - PNH ... Gardner-Diamond syndrome ... • HCV, HBV Not
BEE Syndromes - Non-inflammatory Causes

Immune-mediated conditions affecting the Brain, Eye, and Ear

Visual or auditory symptoms in
Non-inflammatory Causes ... nervous system (CNS ... diagnosis and treatment ... pachymeningitis • HIV ... LHON) plus MRI lesions
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
dementia Pathophysiology ... well-defined than PML lesions ... The clinical syndrome ... Treatment: • HAART ... treatment • Cognitive
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
• Nephrotic Syndrome ... atherosclerotic lesions ... coagulation and other causes ... Venous #Arterial #pathophysiology ... #hematology #differential
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Disease, PRES Pathophysiology ... autoantibodies that will cause ... Puncture, EEG Treatment ... #neurology #rheumatology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
and petechiae Causes ... : - Genetic lesions ... immunodeficiency virus (HIV ... aplastic anemia Treatment ... Anemia #oncology #hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... deficiency) • HIT ... Treat primary cause ... #treatment #management ... #hematology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... of HIV/AIDS patients ... pleural effusions, CNS ... unintentional weight loss, nausea ... #Inflammatory #Syndrome
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
blisters containing pus ... Pustular skin lesions ... Rule out other causes ... and lower jaw Treatment ... #Rheumatology #
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
ischemic skin lesions ... Mucocutaneous lymph node syndrome ... tract, and often causes ... vasculitis • Behcet syndrome ... vasculitis • Cogan syndrome