16 results
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
deficiencies - PNH ... Associated - SLE ... Differential #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Diagnosis and Management ... old, ~10,000 new cases ... acute leukemia Management ... #treatment #hematology ... #oncology
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
#management #algorithm ... #medications #table ... #decisionaid #cardiology ... #hematology #warfarin
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... autoantibodies that will cause ... Erythematosus #SLE ... #rheumatology # ... cerebritis #diagnosis #management
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Discontinuation of causal ... Usual therapeutic management ... #comparison #table ... #rheumatology # ... diagnosis #management
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... lymphocytic lymphoma (SLL ... Lymphocytic Lymphoma (SLL ... #Leukemia #Hematology ... #Oncology #Diagnosis
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
nervous system (CNS ... erythematosus [SLE ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Thromboembolism (7%) • CNS ... Treat primary cause ... Coagulation #diagnosis #causes ... #treatment #management ... #hematology
Polycythemia - Differential Diagnosis Algorithm
Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
an underlying cause ... Better call hematology ... some time, let’s see ... JAK2 V617F) and MPNs ... Algorithm #workup #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
and petechiae Causes ... Aplastic #Anemia #oncology ... #hematology #diagnosis ... #management