32 results
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
Clinically ... suspect underlying hematologic ... Diagnosis and Treatment ... #HES #Hematology ... eosinophils #diagnosis #management
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... old, ~10,000 new cases ... only curative treatment ... Myelodysplastic #Syndrome ... #treatment #hematology
Kerion
Raised, boggy lesion with heaped up purulent nodules 
Caused by host's response to a fungal ringworm
purulent nodules Caused ... mentagrophytes) Clinical ... Lymphadenopathy Treatment ... Griseofulvin #Kerion #Dermatology ... #Diagnosis #Management
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
#management #algorithm ... #pharmacology # ... treatment #medications ... #decisionaid #cardiology ... #hematology #warfarin
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... autoantibodies that will cause ... cerebritis #diagnosis #management ... #treatment
Behcet's Syndrome - Treatment
Ulcers:
 • Treatment: Topical steroids
 • Prevention: Colchicine
 • Azathioprine for refractory disease
Arthritis:
Behcet's Syndrome ... Behcets #disease #Syndrome ... #Treatment #management ... #pharmacology # ... rheumatology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... organ damage • Treatment ... Low calcium • Treatment ... TLS #diagnosis #management ... #hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
organ damage Clinical ... + Bleeding Treatment ... Treat primary cause ... #treatment #management ... #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Clinical Presentation ... nervous system (CNS ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
blisters containing pus ... Rule out other causes ... and lower jaw Treatment ... diagnosis #management ... #Dermatology