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diagnosis treatment algorithm dermatology differential syndrome antinxp2 antinxp2dm arthritis cardiology cerebritis clinical cns coagulation dermatomyositis dic disseminated erythematosus erythrocytosis gout
Causes of Polycythemia (Erythrocytosis) - Differential Diagnosis Algorithm Relative - Normal RBC Mass / Decreased Plasma Volume
Causes of Polycythemia ... Splenomegaly, Increased PMNs ... • Polycythemia ... Diagnosis #Algorithm #Causes ... #Hematology
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
an underlying cause ... Better call hematology ... JAK2 V617F) and MPNs ... about secondary causes ... Algorithm #workup #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... autoantibodies that will cause ... thrombosis and/or blood-brain ... #neurology #rheumatology ... cerebritis #diagnosis #management
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Thromboembolism (7%) • CNS ... Treat primary cause ... Coagulation #diagnosis #causes ... #treatment #management ... #hematology
Gout (Gouty Arthritis) - MSK Radiology Imaging Findings: • Eccentric soft-tissue densities surrounding the third proximal interphalangeal
Arthritis) - MSK Radiology ... Case description ... • PVNS/Giant Cell ... mri #clinical #Radiology ... diagnosis #msk #rheumatology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
blisters containing pus ... Rule out other causes ... SAPHO #Syndrome #Rheumatology ... #diagnosis #management ... #Dermatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... Xerostomia • Dental caries ... Nephrogenic DI Hematologic ... Sjogrens #Syndrome #Rheumatology ... #Diagnosis #Management
Hemophagocytic Lymphohistiocytosis (HLH) Treatment Primary HLH: - HLH-94 Protocol • Dexamethasone
(depending on CNS ... steroids • In mild cases ... Options for severe cases ... HLH #Treatment #management ... #hematology
Acute Recurrent Pericarditis = recurrence of Acute Pericarditis (AP) after free interval >4-6 weeks without symptoms, >1/4
symptoms, >1/4 of AP cases ... Pericarditis #diagnosis #management ... #treatment #rheumatology ... #cardiology
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
subcutaneous edema Pts ... Muscle atrophy may cause ... Dermatomyositis #diagnosis #management ... #rheumatology # ... dermatology
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