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diagnosis management differential oncology algorithm anemia disease myelodysplastic pancytopenia syndromes workup activation bee behcet behcets cerebritis cns dermatology erythematosus lupus
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Aplastic Anemia ... megaloblastic anemia Treatment ... Can progress to MDS ... • Associated PNH ... #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... dys- (abnormal) -plastic ... old, ~10,000 new cases ... #MDS #Diagnosis ... #hematology #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... (MDS) (normal or ... Hypocellular/Hypoplastic MDS ... anemia Treatment ... Anemia #oncology #hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
PNH 2. ... HLH syndrome 5. ... FISH • Acquired Aplastic ... • Hypoplastic MDS ... Diagnosis #Algorithm #Hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
PNH 2. ... HLH syndrome 5 ... FISH • Acquired Aplastic ... • Hypoplastic MDS ... Diagnosis #Algorithm #Hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... autoantibodies that will cause ... Puncture, EEG Treatment ... Maheswaranathan, MD ... #neurology #rheumatology
Behcet's Syndrome - Treatment Ulcers: • Treatment: Topical steroids • Prevention: Colchicine • Azathioprine for refractory disease Arthritis:
Behcet's Syndrome ... - Treatment Ulcers ... : • Treatment: ... Behcets #disease #Syndrome ... #pharmacology #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation Syndrome ... nervous system (CNS ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology ... #Rheumatology
BEE Syndromes - Non-inflammatory Causes Immune-mediated conditions affecting the Brain, Eye, and Ear Visual or auditory symptoms in
Non-inflammatory Causes ... nervous system (CNS ... diagnosis and treatment ... consistent with MS ... #neurology #noninflammatory
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
(MDS) What? ... Out Secondary Causes ... • Anemia • Aplastic ... factor (GCSF) treatments ... #diagnosis #hematology
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