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diagnosis management syndrome clinical mds myelodysplastic table algorithm anthracycline apml brain cardiomyopathy cardiotoxicity chemotherapy comparison criticalcare crypto cryptococcal differential differentiation
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
old, ~10,000 new cases ... • Risks: infection ... transformation to acute ... only curative treatment ... #hematology #oncology
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
without other cause ... : 33% • Treatment ... : Age>60, CKD, CHF ... At least 3 of (Acute ... Transfusion #Reactions #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... Attempt if high risk ... sepsis), PE, DAH, CHF ... diagnosis #management #hematology ... #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... -> AML: Blast crises ... Transformation: • Complication ... #Leukemia #Hematology ... #Oncology #Diagnosis
Peripartum Cardiomyopathy - Summary 1. Definition • Towards the end of pregnancy to 5 months postpartum
exclude other causes ... May have typical HF ... Thromboembolic complications ... diagnosis #management #cardiology ... #treatment
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
important to recognize Acute ... the determined cause ... algorithm #management #cardiology ... #heartfailure #chf ... icu #clinical #pharmacology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
carries a variable risk ... and reducing the risk ... factors (examples: G-CSF ... Syndromes #diagnosis #hematology ... #oncology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
effusion, INC risk ... Nephrogenic DI Hematologic ... Malignancy Risk ... Adenocarcinoma Treatment ... lubricants • Pharmacologic
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
Summary of Oncologic ... syndrome): - Hematologic ... mg/dL or > 25 % rise ... Treat underlying cause ... interventional radiology
Cryptococcal meningitis on T2 MRI 30 M from sub-Saharan Africa presents w/ progressive Headache x1 mo, +neck
Nausea & vomiting ... Standard treatment ... performed, relative risk ... have a higher risk ... Brain #clinical #radiology
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