34 results
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
old, ~10,000 new cases ... diagnosis and risk-stratification ... • Risks: infection ... #treatment #hematology ... #oncology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
= nonspecific (nausea ... Intrahepatic Cholestasis Management ... Monitor and Treat Complications ... Liver #Pregnancy #hepatology ... obgyn #diagnosis #management
Post-MI Free Wall Rupture
1. What's the role of revascularization when presenting with late STEMI?
2. What are
What are some causes ... What are the risk ... pursue surgical management ... FreeWall #Rupture #cardiology ... #complications
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... count ↑ PLT • ↑ PBS ... Transformation: • Complication ... #Leukemia #Hematology ... #Oncology #Diagnosis
Treatment Schema for Standard-Risk Acute Lymphoblastic Leukemia
Induction: 
 • Vincristine, Steroid (dexamethasone), L-Asparaginase, Intrathecal (IT) methotrexate
Consolidation
Schema for Standard-Risk ... Consolidation & CNS ... Cytarabine #ALL ... Treatment #timeline #oncology ... pediatrics #peds #management
Treatment algorithm for VTE in Malignancy

(A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
patients at high risk ... also balance the risk ... VTE and bleeding complications ... Anticoagulation #Management ... #Hematology #Oncology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Most cases diagnosed ... prematurely • risk ... membrane into the CNS ... Phosphatase: • Other causes ... Hyophosphatasia #hepatology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
• Acquired Risk ... considered in all ... cardiovascular risk ... coagulation and other causes ... pathophysiology #hematology
Iron Deficiency in Heart Failure
Pathophysiology:
Chronic heart failure leads to an increase in inflammatory cytokines → Inflammation
→ Inflammation causes ... showed reduced risk ... composite endpoint of all-cause ... heartfailure #diagnosis #management ... #cardiology
Post-Transplantation Lymphoproliferative Disorders (PTLD)
Definition: Lymphoid and/or plasmacytic proliferations that occur as a result of immunosuppression in
accounts for 21% of all ... immunocompetent population Risk ... symptoms, unexplained hematologic ... Lymphoproliferative #Disorders #oncology ... #diagnosis #management