15 results
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
old, ~10,000 new cases ... • Risks: infection ... transformation to acute ... only curative treatment ... #hematology #oncology
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
neutropenic fever) Complications ... Can progress to MDS ... or acute leukemia ... • Associated PNH ... #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
ALL (Acute Lymphoblastic ... -> AML: Blast crises ... Transformation: • Complication ... #Leukemia #Hematology ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
thrombocytopenia Complications ... chemotherapy for low-risk ... Lauren Banaszak, MD ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Incidence: common in APL ... Triggers: ATRA treatment ... Attempt if high risk ... diagnosis #management #hematology ... #oncology
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
normal in mild cases ... - Acute Bleeding ... Avoid meds that ... ↑ bleeding risk ... #hematology
Peripartum Cardiomyopathy - Summary
1. Definition
 • Towards the end of pregnancy to 5 months postpartum
exclude other causes ... • Minority of Pts ... Thromboembolic complications ... diagnosis #management #cardiology ... #treatment
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
involve one, two, or all ... carries a variable risk ... and reducing the risk ... Syndromes #diagnosis #hematology ... #oncology
Essential Thrombocythemia (ET)
ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
Most cases are related ... , symptoms and complications ... PV, MDS, CML) Treatment ... Thrombocythemia #ET #hematology ... diagnosis #management #hematology
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
syndrome): - Hematologic ... mg/dL or > 25 % rise ... Treat underlying cause ... interventional radiology ... AML (~20 %) and APL