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diagnosis management infectiousdiseases aspergillus coccidioidomycosis hemeonc rheumatology abscess betadglucan biomarkers brain candida candidemia candidiasis cardiomyopathy chronic classification cll comparison crypto
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
Fungal Biomarkers ... dermatophytes, Coccidioides ... infection (IFI) in hematologic ... cut-offs defined in clinical ... useful in high risk
Candidemia Workup and Management - IDSA Guidelines 1) Antibiotics • Empiric: Echinocandins (e.g. micafungin) for most patients
Other hardware - Risk-Benefit ... or TEE unless clinical ... Consider: Spine, CNS ... #candidiasis #treatment ... #fungal #fungemia
Invasive Aspergillus (IA) - Diagnosis and Management Aspergillus is ubiquitous in nature. Most invasive infections are caused
infections are caused ... complex Classic Risk ... HIV/AIDS, CGD) Clinical ... this morphology Treatment ... #fungal #infectiousdiseases
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
immunophenotype Clinical ... thrombocytopenia Complications ... chemotherapy for low-risk ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
• Most common cause ... pneumonia • DM risk ... Lung Abscess - Clinical ... Prevotella • Fungal ... Cryptococcus - Coccidioides
Peripartum Cardiomyopathy - Summary 1. Definition • Towards the end of pregnancy to 5 months postpartum
exclude other causes ... remains unknown • Final ... Thromboembolic complications ... diagnosis #management #cardiology ... #treatment
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
> 4 days → add fungal ... syndrome): - Hematologic ... mg/dL or > 25 % rise ... Treat underlying cause ... interventional radiology
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
MUCORMYCOSIS • Risk ... has five major clinical ... stain of clinical ... Encapsulated yeast • At risk ... • Serology for Coccidioides
Coccidioidomycosis (Coccidioides): Valley Fever - Summary Sheet • Morphology • Geography, Reservoir and Mode of Transmission
Coccidioidomycosis (Coccidioides ... Americans at higher risk ... disseminated disease • Clinical ... tissue, skeleton, CNS ... management #summary #fungal
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... salivary ducts Clinical ... effusion, INC risk ... Malignancy Risk ... Adenocarcinoma Treatment
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