37 results
Recurrent / Breakthrough DVT During Anticoagulation

Subtherapeutic Anticoagulation
Hypercoagulable State 
 - Antithrombin deficiency 
 - Hypercoagulability ot
Breakthrough DVT During Anticoagulation ... Subtherapeutic Anticoagulation ... APLS - MPN/PNH ... Structural - Pelvic masses ... #hematology #differential
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... : - Thrombocytopenia ... Differential #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Bleeding risk calculators - HAS-BLED (atrial fibrillation) and IMPROVE (VTE prophylaxis for inpatients)
Important notes:
 • No
studies suggest net clinical ... benefit of anticoagulation ... of withholding anticoagulation ... #Calculators #Anticoagulation ... #Factors #Hematology
4-T Score for the Likelihood of Heparin Induced Thrombocytopenia
 - Thrombocytopenia - Compare the highest platelet
count
Other potential cause ... Low probability (risk ... Intermediate probability (risk ... High probability (risk ... Likelihood #Diagnosis #Hematology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Causes of Bleeding ... Diagnosis Algorithm Thrombocytopenia ... - Acquired • Anticoagulation ... Diagnosis #Algorithm #Causes ... #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Causes of Thrombocytopenia ... l MD SOAP) - Risks ... of thrombocytopenia ... or if a primary hematologic ... #Workup #hematology
Von Willebrand Disease - Most common inherited bleeding disorder 
Clinical 
 • Easy bruising 
 •
bleeding disorder Clinical ... bruising • Skin ... platelet count (mild thrombocytopenia ... Disease #Diagnosis #Hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
• Acquired Risk ... Testosterone - Coumadin skin ... cardiovascular risk ... Heparin-induced thrombocytopenia ... pathophysiology #hematology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
arterial thrombosis, skin ... injection sites) ↑ Risk ... Diagnosis: • Clinical ... exposure (prevent skin ... Management #Treatment #Hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
organ damage Clinical ... Thromboembolism (7%) • CNS ... Treat primary cause ... Coagulation #diagnosis #causes ... treatment #management #hematology