12 results
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... dys- (abnormal) -plastic ... old, ~10,000 new cases ... • Risks: infection ... #treatment #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Constitutional Syndromes ... and petechiae Causes ... anemia Treatment ... Anemia #oncology #hematology ... #diagnosis #management
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... • Triggers: Diuretics ... into serum • Triggers ... TLS #diagnosis #management ... #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... autoantibodies that will cause ... #neurology #rheumatology ... cerebritis #diagnosis #management ... #treatment
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
the study) • Triggers ... : ATRA treatment ... Attempt if high risk ... APML #diagnosis #management ... #hematology #oncology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Nephrogenic DI Hematologic ... phenomenon (16%) MSK ... Adenocarcinoma Treatment ... #Rheumatology # ... Diagnosis #Management
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
carries a variable risk ... • Anemia • Aplastic ... factor (GCSF) treatments ... and reducing the risk ... #diagnosis #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Treatment
Primary HLH:
 - HLH-94 Protocol
    • Dexamethasone
Lymphohistiocytosis (HLH) Treatment ... (depending on CNS ... varies depending on trigger ... autoimmune disease, treatment ... #management #hematology
Clarkson’s Disease - Capillary leak syndrome
Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
Capillary leak syndrome ... vascular filling +++ (risk ... Prevention of at-risk ... #diagnosis #management ... #rheumatology
Trigger Finger - Stenosing flexor tendon tenosynovitis

There is a change in the slip between the tendon
Trigger Finger - ... diabetes is a risk ... one shown in the video ... tenosynovitis #msk ... #orthopedics #rheumatology