PNS hematology causes risk rheumatology treatment workup diagnosis syndrome table dermatology lupus

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Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells

Myelodysplastic Syndrome ... old, ~10,000 new cases ... and risk-stratification ... • Risks: infection ... #hematology #oncology

Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?

→ Refer to hematology ... for workup, including ... Rebound effect from treatment ... Kawasaki, Nephrotic syndrome ... #Algorithm #hematology

CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic

Demyelinating Syndrome ... autoantibodies that will cause ... permeability Diagnosis ... #neurology #rheumatology ... #cerebritis #diagnosis

Connective tissue disease-associated interstitial lung diseases

LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.

PSS: Sjogren syndrome ... SLE : systemic lupus ... LungDisease #CTILD #Diagnosis ... Differential #Comparison #Table ... #Pulmonary #Rheumatology

Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
1. Autoimmune Mediated Pancytopenia
2. Splenic Sequestration
Peripheral Destruction

Pancytopenia - Workup ... and Differential Diagnosis ... PNH 2. ... HLH syndrome 5. ... #Algorithm #Hematology

Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage

- Differential Diagnosis ... Kasabach-Merritt syndrome ... deficiencies - PNH ... #hematology #rheumatology ... #nonpalpable #dermatology

Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition

Causes of Hypocomplementemia ... antiphospholipid syndrome ... S - Systemic Lupus ... CHAMPS #Mnemonic #diagnosis ... #differential #hematology

Dyspnea - Differential Diagnosis Framework

Cardiovascular Causes of Dyspnea:
• Myocardium:
- Heart failure
- CAD/ACS
- Valvulopathy
• Electrical:
-

- Differential Diagnosis ... - Water - Pus ... Hepatopulmonary syndrome ... Transverse myelitis • Hematology ... #differential #diagnosis

Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
• Mechanical Trauma (Microangiopathic hemolytic anemia):

Diagnostic Framework ... Extravascular Causes ... hemoglobinuria (PNH ... usually IgG) (e.g. lupus ... #hematology #anemia

Pancytopenia - Workup ... and Differential Diagnosis ... PNH 2. ... HLH syndrome 5 ... #Algorithm #Hematology

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