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diagnosis differential anemia hemolytic extravascular intravascular antiphospholipid apls enlarged erythrocytosis hypercoagulable spleen splenomegaly syndrome testing
Hemolysis - Diagnostic Algorithm and Causes Increased red cell production: • Increased Reticulocytosis/polychromasia • Erythroid
Hemolysis - Diagnostic ... Algorithm and Causes ... #Algorithm #Differential ... #Causes #Workup ... #Hematology #Diagnosis
Causes of Splenomegaly - Differential Diagnosis Algorithm Infectious • Bacterial • Viral (EBV) • Parasitic • Fungal Congestive
Differential Diagnosis Algorithm ... disorders (eg. polycythemia ... Inflammatory • Systemic Lupus ... Serum Sickness Hemolytic ... #Causes #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... hemoglobinuria (PNH ... usually IgG) (e.g. lupus ... Extravascular #Causes ... differential #diagnosis #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... Differential Diagnosis Algorithm ... • PCH • PNH ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Causes of Polycythemia (Erythrocytosis) - Differential Diagnosis Algorithm Relative - Normal RBC Mass / Decreased Plasma Volume
Causes of Polycythemia ... Differential Diagnosis Algorithm ... Splenomegaly, Increased PMNs ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Diagnosis Algorithm ... Better call hematology ... JAK2 V617F) and MPNs ... about secondary causes ... #workup #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Differential Diagnosis Algorithm ... platelet decrease - PNH ... Differential #Diagnosis #Algorithm ... #workup #hematology
Antiphospholipid Syndrome (APLS) Testing - Hypercoagulable Workup Algorithm INDICATIONS FOR TESTING: • Vascular thrombosis
Hypercoagulable Workup ... Algorithm INDICATIONS ... maternal chromosomal causes ... excluded Testing: • Lupus ... #hematology
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