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diagnosis differential anemia hemolytic extravascular intravascular antiphospholipid apls clots crisis dermatology enlarged hypercoagulable management nephrology nonpalpable palpable purpura renal scleroderma
Hemolytic Anemia - Hemolysis Diagnostic Workup Infographic by: Howard Ong #Hemolysis #Hemolytic #Anemia #Algorithm #MAHA #TTP #Diagnosis #Workup
Hemolytic Anemia ... Workup Infographic ... #Algorithm #MAHA ... #TTP #Diagnosis ... #Workup #Hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... • PCH • PNH ... Shearing • MAHA ... (TTP, DIC, HUS) ... #Causes #Hematology
Causes of Arterial and Venous Thrombosis - Differential Diagnosis Framework STRUCTURAL: - PFO: paradoxical emboli - Popliteal
Causes of Arterial ... artery aneurysm: Causes ... neoplasms - PNH ... - HIT - MAHA ... Diagnosis #clots #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... thrombocytopenic purpura (TTP ... hemoglobinuria (PNH ... usually IgG) (e.g. lupus ... differential #diagnosis #hematology
Causes of Splenomegaly - Differential Diagnosis Algorithm Infectious • Bacterial • Viral (EBV) • Parasitic • Fungal Congestive
Differential Diagnosis Algorithm ... Infectious • Bacterial ... Inflammatory • Systemic Lupus ... Serum Sickness Hemolytic ... #Causes #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Differential Diagnosis Algorithm ... platelet decrease - PNH ... thrombocytopenia - DIC, TTP ... Differential #Diagnosis #Algorithm ... #workup #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
/HUS - Hemolytic ... Defects: • DIC, TTP ... deficiencies - PNH ... Differential #Diagnosis #hematology ... #rheumatology #
Scleroderma Renal Crisis (SRC) Clinical Presentation of Scleroderma Renal Crisis: 1) Acute kidney injury 2) Abrupt onset of hypertension 3)
microangiopathic hemolytic ... anemia (MAHA) ... onion-skinning" of arteries ... PLEX (overlap TTP ... Renal #Crisis #rheumatology
Antiphospholipid Syndrome (APLS) Testing - Hypercoagulable Workup Algorithm INDICATIONS FOR TESTING: • Vascular thrombosis
Hypercoagulable Workup ... clinical episodes of arterial ... maternal chromosomal causes ... excluded Testing: • Lupus ... #hematology
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