27 results
diagnosis management differential lupus oncology algorithm erythematosus hemophagocytic lymphohistiocytosis syndrome systemic druginduced leukemia neurology summary activation anemia aortitis arterial behcet
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Autoimmune • ITP • SLE ... Alloimmune • anti-HLA ... HUS • DIC • Vasculitis ... #Hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
: - Thrombocytopenia ... deficiencies - PNH ... Associated - SLE ... Differential #Diagnosis #hematology ... #rheumatology #
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Causes of Thrombocytopenia ... Diagnosis and Workup ... test, ANA (e.g., SLE ... or if a primary hematologic ... #Workup #hematology
Dyspnea - Differential Diagnosis Framework Cardiovascular Causes of Dyspnea: • Myocardium: - Heart failure - CAD/ACS - Valvulopathy • Electrical: -
Cardiovascular Causes ... - Water - Pus ... Pulmonary HTN - Vasculitis ... Barre - ALS - Transverse ... myelitis • Hematology
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Non-Infectious Aortitis: • Vasculitides ... ANCA associated vasculitis ... erythematosus (SLE ... , Sarcoidosis, HLA-B27 ... Differential #Diagnosis #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
erythematosus [SLE ... leukopenia, anemia, and thrombocytopenia ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology ... #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Autoimmune diseases: SLE ... Drugs, Unknown cause ... Treatment: • ... diagnosis #management #treatment ... #summary #rheumatology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
genotypes): SS, SC, SE ... Schistocytes, thrombocytopenia ... cardiac valve, vasculitis ... Diagnosis #Algorithm #workup ... #hematology #testing
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Erythematosus (SLE ... • Immunologic Workup ... Positive in 60-80% of cases ... life-threatening • Treatment ... Management #Summary #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Treatment Primary HLH: - HLH-94 Protocol • Dexamethasone
) Treatment Primary ... (depending on CNS ... autoimmune disease, treatment ... #Treatment #management ... #hematology
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