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diagnosis comparison differential management aflp anemia disease hemolysis hemolytic obstetrics pregnancy thrombocytopenia ttphus agglutinin behcet dermatology dyspnea extravascular intravascular obgyn
Dyspnea - Differential Diagnosis Framework Cardiovascular Causes of Dyspnea: • Myocardium: - Heart failure - CAD/ACS - Valvulopathy • Electrical: -
- Asthma - COPD ... - Water - Pus ... Hepatopulmonary syndrome ... Barre - ALS - Transverse ... myelitis • Hematology
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP) Three syndromes in
Syndrome and Acute ... Elevated Liver tests ... child * Severe cases ... AFLP #obstetrics #hematology ... #diagnosis #table
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... coagulation (DIC) - HELLP ... syndrome - ... hemoglobinuria (PNH ... differential #diagnosis #hematology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
TTP, HUS, DIC, HELLP ... Autoimmune: Warm AIHA, Cold ... Drug-associated, PCH, Evans Syndrome ... Laboratory Tests ... Differential #Diagnosis #hematology
Cold Urticaria Prevalence - 0.05% in the population Disease onset - Mostly 2nd to 4th decades of life Causes
decades of life Causes ... and clinical associations ... - Ice cube test ... Urticaria #diagnosis #rheumatology ... #comparison #table
Thrombocytopenia and Pregnancy Three syndromes in the critically ill pregnant woman who presents with coagulation defects. 1) HELLP
Pregnancy Three syndromes ... Elevated Liver tests ... child * Severe cases ... Obstetrics #OBGyn #Hematology ... Diagnosis #Comparison #Table
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Agglutinin Syndrome ... Viral Infection Clinical ... • Diagnostic Test ... Donath-Landsteiner test ... hemolytic #anemia #hematology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
association • M > F Clinical ... matter, spinal cord ... (Clinical Dx). ... is a skin prick test ... signs #symptoms #rheumatology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
blisters containing pus ... Rheumatic pain Clinical ... Diagnosis: • A clinical ... Rule out other causes ... #Rheumatology #
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... salivary ducts Clinical ... peripheral neuropathy, transverse ... Nephrogenic DI Hematologic ... #Rheumatology #
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