10 results
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... : - ANA > ... : - ANA > ... Lupusreference #druginduced ... #table #rheumatology
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Syndrome and Acute ... Pregnancy (AFLP) Three syndromes ... child * Severe cases ... AFLP #obstetrics #hematology ... #diagnosis #table
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... coagulation (DIC) - HELLP ... syndrome - ... usually IgG) (e.g. lupus ... differential #diagnosis #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Demyelinating Syndrome ... autoantibodies that will cause ... Erythematosus #SLE #CNS ... #neurology #rheumatology
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Pregnancy Three syndromes ... coagulation defects. 1) HELLP ... child * Severe cases ... Obstetrics #OBGyn #Hematology ... Diagnosis #Comparison #Table
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Non-autoimmune rheumatologic ... • May involve PNS ... and CNS • Headache ... neuropathy • Transverse ... Erythematosus #Diagnosis #Rheumatology
Polycythemia - Differential Diagnosis Algorithm
Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
underlying cause ... Better call hematology ... MPNs (MPL, CALR ... expert around to help ... #hematology
Drug Induced Lupus (DIL)
 • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
Drug Induced Lupus ... • Immunologic Workup ... Discontinuation of causal ... Lupusreference #DrugInduced ... #Lupus #DIL #rheumatology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... Hypocomplementemia • Can cause ... peripheral neuropathy, transverse ... Nephrogenic DI Hematologic ... #Rheumatology #
Antiphospholipid Syndrome (APLS) Testing - Hypercoagulable Workup Algorithm
INDICATIONS FOR TESTING:
 • Vascular thrombosis
Antiphospholipid Syndrome ... Hypercoagulable Workup ... chromosomal causes ... excluded Testing: • Lupus ... Algorithm #diagnosis #hematology