22 results
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
Cauda Equina Syndrome ... • Infection (abscess ... #MSK #pathophysiology ... #diagnosis #symptoms ... #signs
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Dehydration • Symptoms ... WBC >100k, + lab signs ... : • Pathophysiology ... #TLS #diagnosis
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
- Differential Diagnosis ... and signs below ... , HIV, CMV, HTLV ... TB - Spinal abscess ... MCTD, Sjogren syndrome
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
- Differential Diagnosis ... cells per μL • Diagnosis ... Antimicrobial treatment ... tuberculomas, or abscesses ... opportunistic #InfectiousDiseases
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... Signs and symptoms ... Multiple Sclerosis Treatment ... • Acute: - IV ... management #neurology #treatment
Cauda Equina Syndrome Overview

Cauda Equina Syndrome:
 • Prevalence: 1:33,000-100,000 ppl/yr
 • Incidence: 1.5-3.4 million ppl/yr
 •
spine L1-L5 Symptoms ... Differential Diagnosis ... cord infarct • HIV ... Spinal infection/abscess ... axial T1 and T2 Treatment
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
dementia Pathophysiology ... • Depressive symptoms ... Diagnosis: MRI ... The clinical syndrome ... Treatment: • HAART
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Pathophysiology ... : >3 symptoms, or ... • Steroids: IV
Signs and Symptoms Associated With Different Headache Etiologies
 • Nonfocal mental status changes - Meningitis, encephalitis,
Signs and Symptoms ... aneurysm, bleed, abscess ... deficits (CN Ill, IV ... #symptoms #clues ... #differential #diagnosis
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Lady Windermere Syndrome ... : • Syndrome of ... mucogenicum • HIV ... Advanced HIV (CD4 ... #infectiousdiseases