39 results
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
Clinically ... disorders • Diagnosis ... #HES #Hematology ... #eosinophils #diagnosis ... #management #algorithm
Susac Syndrome - Clinical Triad
 - Central nervous system dysfunction
 - Branch retinal artery occlusion
 -
Susac Syndrome - ... Clinical Triad ... artery occlusion ... SusacSyndrome #Triad #Diagnosis ... #Management #Rheumatology
92F w acute painless monocular vision loss. What's the diagnosis?

...

Central retinal artery occlusion (CRAO)! Retrobulbar "spot
What's the diagnosis ... Central retinal ... artery occlusion ... #Clinical #POCUS ... #OcularUS #CRAO
Behcet's Syndrome - Diagnosis
Diagnostic Criteria for Behget's Syndrome (International Study Group for Behget's Disease):
 • Recurrent,
- Diagnosis Diagnostic ... disease: Uveitis or retinal ... test Most Common Clinical ... (e.g. uveitis, retinal ... #criteria #rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... disease (SVC/IVC occlusion ... (Clinical Dx). ... #diagnosis #management ... signs #symptoms #rheumatology
Diagnosis of Cryoglobulinemia Vasculitis

1) Presence of cryoglobulin 
Circulating immunoglobulins that precipitate with cold temperature and dissolve
not related to clinical ... l) : Vascular occlusion ... Hyperviscosity syndrome ... arthritis • Renal ... #Rheumatology #
Myositis Specific Antibodies (MSAs)

Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE
Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ
Immune Mediated
Anti-Synthetase Syndrome ... ): HMGCR, SRP Inclusion ... Antibodies #MSAs #clinical ... #diagnosis #rheumatology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
pulmonary emboli, and ocular ... thrombi including retinal ... Antiphospholipid syndrome ... #rheumatology # ... hematology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
severe disease & renal ... block • Sjogren syndrome ... #SLE #Summary #diagnosis ... #rheumatology # ... management
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... Differential Diaqnoses ... • Ocular: uveitis ... #management #treatment ... #rheumatology