15 results
Drug-Induced Acute Kidney Injury - Sites of Action Along the Nephron

#DrugInduced #AcuteKidneyInjury #AKI #Nephrology #Pathophysiology #Pharmacology
Drug-Induced Acute ... AKI #Nephrology #Pathophysiology ... #Pharmacology
Drug-Induced Edema
Drug-induced edema is caused by many drugs & can coincide with or worsen pre-existing peripheral
Drug-Induced Edema ... Drug-induced edema ... blood vessels Drug-induced ... #Differential #Pharmacology ... #Pathophysiology
Drug-Induced Seizures - OTIS-CAMPBELL

O - Organophosphate, oral hypoglycemics, opioid
T - TCA, theophylline
I - Isoniazid, Insulin
S -
Drug-Induced Seizures ... /insecticides, PCP ... Kat_Watson #Drug ... #Induced #Seizures ... #Differential #Pharmacology
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Mechanisms of Drug-Induced ... differential #diagnosis #pathophysiology ... #pharmacology #
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Biliary Cirrhosis (PBC ... ) - Summary PBC ... 30-65 years PBC ... Pathophysiology ... , Sarcoidosis, Drug-induced
Treatment of Obstructive Sleep Apnea
Positive airway pressure therapy
   → Positive pharyngeal transmural pressure
Mandibular advancement devices ... unfavorable collapse on drug-induced ... Treatment #management #pulmonary
Widened Pulse Pressure - Differential Diagnosis and Pathophysiology

Pulse pressure is the difference between the systolic blood
Diagnosis and Pathophysiology ... deficiency anemia (reduced ... disorders - Chronic pulmonary ... Infarction • Pulmonary ... Differential #Diagnosis #Pathophysiology
Asthma Maintenance Therapy - Stepwise Approach 

Low dose ICS 
-> Low dose ICS/LABA or Med/High dose
primary maintenance drug ... The device is the ... Therapy #Management #Pharmacology ... #Pulmonary
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... endothelial damage • Induce ... Imaging: CXR- pulmonary ... fluid overload, PCC
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
hypoperfusion - toxic-induced ... www.ncbi.nlm.nih.gov/pmc ... circulation If drugs ... output - Acute pulmonary ... Alcohol • Type B2: Drugs