66 results
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Peripheral Smear ... hematologic: Acute blood ... Vasculitides, IBD, Celiac disease ... Kawasaki, Nephrotic syndrome ... pancreatitis, Post-surgical
Adjuvant therapies in critical care: steroids to treat infectious diseases
 - Severe Community Acquired Pneumonia
steroids to treat infectious ... diseases - Severe ... respiratory distress syndrome ... Corticosteroids #Adjuvant #InfectiousDiseases ... #Management #Treatment
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Immunoglobulin M (IgM) • Blood ... smear - RBC agglutination ... Polyclonal IgM post ... sensitize red blood
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Drug-associated, PCH, Evans Syndrome ... , Drugs, Liver Disease ... Internal (RBC) - Infections ... - Peripheral Blood ... Smear ↑ abnormal
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Phagocytosis of blood ... • Autoimmune diseases ... Adult-onset Still disease ... chemotherapy, anti-CD20 (PTLD ... Lymphohistiocytosis #diagnosis #management
Disseminated Gonococcal Infection - Diagnosis and Management Summary

Bacteremic spread of the Gram-negative diplococci Neisseria gonorrhoeae. History
Diagnosis and Management ... : • 2 sets of blood ... Purulent Arthritis Syndrome ... : • Most patients ... #Microbiology #InfectiousDiseases
Listeriosis Summary - Listeria Monocytogenes
Pathogen: Listeria Monocytogenes - Gram-positive rod, Aerobic, facultative anaerobe, motile, beta-hemolytic, Non-spore-forming
Risk
available • Blood ... culture (Invasive disease ... ) • CSF (CNS Infection ... Monocytogenes #diagnosis #management ... #infectiousdiseases
Listeriosis Summary - Listeria Monocytogenes
Pathogen: Listeria Monocytogenes - Gram-positive rod, Aerobic, facultative anaerobe, motile, beta-hemolytic, Non-spore-forming
Risk
available • Blood ... culture (Invasive disease ... ) • CSF (CNS Infection ... Monocytogenes #diagnosis #management ... #infectiousdiseases
Problem Representation - Approach to the Infectious Disease Patient

Who: Patient age and host/risk factors (such as
Approach to the Infectious ... Disease Patient ... Patient age and host ... define the clinical syndrome ... febrilepodcast@gmail.com #InfectiousDiseases
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
other cancers: Most ... and M panel Management ... : • Nephrotic syndrome ... (Epstein-Barr syndrome ... hematology #diagnosis #management