70 results
differential hematology treatment causes microbiology rheumatology classification clinical dermatology fever algorithm chagas hemeonc hemophagocytic hiv hlh leukemia lymphohistiocytosis myelodysplastic neurology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
peripheral blood smear ... extramedullary disease ... • Peripheral smear ... Leukemia #Hematology #Oncology ... #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
: • Most common ... weeks without infection ... • Peripheral smear ... cells can indicate disease ... #workup #oncology
Post-Transplantation Lymphoproliferative Disorders (PTLD) Definition: Lymphoid and/or plasmacytic proliferations that occur as a result of immunosuppression in
Post-Transplantation ... extralymphatic tissues Diagnosis ... #Post #Transplantation ... Lymphoproliferative #Disorders #oncology ... #diagnosis #management
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin Syndrome ... lymphoid malignancy (CLL ... IgM) • Blood smear ... Polyclonal IgM post ... malignancies -> CLL
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... ) - HELLP syndrome ... Hemolytic uremic syndrome ... ) (e.g. lupus, CLL ... antibiotics are the most
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... risk-stratification • Risks: infection ... Allogeneic stem cell ... Myelodysplastic #Syndrome ... #hematology #oncology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
lymphoma, B-cell ... • Autoimmune diseases ... Adult-onset Still disease ... chemotherapy, anti-CD20 (PTLD ... #management #treatment
Disseminated Gonococcal Infection - Diagnosis and Management Summary Bacteremic spread of the Gram-negative diplococci Neisseria gonorrhoeae. History
Management Summary ... Purulent Arthritis Syndrome ... : • Most patients ... #Management #Microbiology ... #InfectiousDiseases
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... Peripheral Smear ... Vasculitides, IBD, Celiac disease ... Kawasaki, Nephrotic syndrome ... #Differential #Diagnosis
Cutaneous manifestations associated with myelodysplastic syndrome • Myeloid hemopathy with the most frequent skin lesions (20%)
hemopathy with the most ... appearing during the disease ... Infectious manifestations ... #differential #diagnosis ... #dermatology #oncology
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