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diagnosis coagulation differential laboratory pt causes abnormal disseminated intravascular bleeding bruising disorders hemostasis hepatic hepatology isth liverfailure management partial ppt
Causes of Prolonged PT (INR), Prolonged PTT • Prolonged PT (INR), Prolonged PTT • Prolonged PT
PT (INR), Prolonged ... PTT • Prolonged ... PT (INR), Prolonged ... PTT • Prolonged ... PTT • Prolonged
Algorithm for Investigation of Abnormal Coagulation Tests - Prolonged PT - Prolonged aPTT and Prolonged PT - Prolonged aPTT Dr.
PT - Prolonged ... aPTT and Prolonged ... PT - Prolonged ... #Laboratory #Hematology ... #Diagnosis #Workup
Prothrombin Time (PT) and Partial Thromboplastin Time (PTT) Prothrombin Time (PT) - Often Elevated in: • Vitamin
Thromboplastin Time (PTT ... Thromboplastin Time (PTT ... in: • DIC • ... #PTT #Prothrombin ... Thromboplastin #laboratory #hematology
Approach to Elevated aPTT / PT - Differential Diagnosis Algorithm aPTT: Intrinsic / Final PT: Extrinsic / Final By
Approach to Elevated ... aPTT / PT - Differential ... / Final PT: Extrinsic ... #aPTT #PT #INR ... #Algorithm #Hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Thrombocytopenia • Prolonged ... PT/PTT • Low ... fibrinogen • Elevated ... /INR: ↑ • PTT: ... < 2.3 - APTT
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
PT and aPTT If ... the PT and the ... aPTT are both prolonged ... #Abnormal #PT ... #aPTT #Prolonged
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC) Platelet count: • Expected: Low (or normal) • Elevation
platelet aggregation PT ... , aPTT: • Expected ... monitor using INR ... use PT D-dimer ... Scoring #diagnosis #hematology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
/NORMAL PTT: • ... /ABNORMAL PTT: ... Perform a PTT mixing ... /NORMAL PTT: Suggests ... PTT suggests liver
Commonly Observed Laboratory Findings in Hepatic / Liver Failure - Elevated conjugated and unconjugated bilirubin -
Liver Failure - Elevated ... glycogen stores - Prolonged ... PT - Decreased ... As a result of DIC ... LiverFailure #Hepatic #Hepatology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
be performed PT ... , PTT, and fibrinogen ... Normal or slightly elevated ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup ... #Hematology
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